Nathan C. Frey

Hi, I’m Nathan! I lead drug discovery and development research at Anthropic. Before that, I co-founded Coefficient Bio, where we figured out how to make biotech company creation and operation hill-climbable.

I’m interested in creating and using powerful AI systems to help scientists develop new medicines to cure disease, slow down or reverse aging, and improve the human condition. My team is building “pipeline-in-a-person” to enable a single skilled biotech operator + a bunch of Claudes to create and operate drug programs. We’re focused on making Claude the best model for biotech.

I was a group leader at Genentech, where I worked on lab-in-the-loop for therapeutic antibody design, discrete diffusion, interpretability, and foundation models for drug discovery. Before that, I did a PhD in Materials Science & Engineering at the University of Pennsylvania as an NDSEG fellow, and was a postdoctoral fellow at MIT. I occasionally write on the internet.